Educational information, not medical advice.See how evidence is graded

Face goes red after wine

You take a few sips of wine. Within minutes, your cheeks and nose feel hot. In the mirror, the skin looks pink or blotchy.

Alcohol widens the tiny blood vessels in your face. Some people flush far more than others. If the redness lasts for hours, or keeps coming back, it may be rosacea, a long-term skin condition that brings on flushing.

Red wine is a common trigger. So are heat, spicy food, stress, and hot drinks. Flushing can also come from the way your body breaks down alcohol, which is common in people of East Asian descent.

When to see someone

See a doctor if the redness stays for days, or if your face burns and stings. Bumps, pimples, visible veins, or thick skin on your nose also need a look. Get care fast for eye pain, gritty or blurred vision, a swollen face or lips, hives, or trouble breathing after a drink.

How to read the grades below

Below you will find remedies that people use for rosacea. Each one carries a grade for the strength of the research behind it. A high grade means more study has been done; a low grade means little or none.

Rosacea: natural remedies and the evidence behind them

9 options · 1 graded A · 1 graded B · 1 graded C · 6 traditional or ungraded

How is my rosacea showing up, and what kind of help am I looking for?

Bumps and pimple-like breakouts, not just redness

  1. Azelaic acid

    Supported by controlled trials· Centuries of traditional use (Evidence grade A · Traditional use long-standing)Long-standing traditional staple

    Well-evidenced topical for inflammatory rosacea

    Why it may be relevant
    When rosacea shows bumps and inflamed spots, azelaic acid is a commonly chosen topical — the library lists rosacea among the conditions it helps.
    Why try it
    Azelaic acid is a naturally occurring acid found in grains like barley, wheat, and rye. It is one of the best-evidenced options for the bumps and pustules of rosacea: a systematic review of randomized controlled trials found topical azelaic acid helps reduce inflammatory lesions and even out skin tone. Introduce it gradually, as it can sting at first.
    Dose or use
    Follow product labeling; apply a thin layer to affected areas. Consult a healthcare practitioner.
    Time to results
    Typically 4-12 weeks
    Key study
    Systematic Review (2023, PMID 37550898): A systematic review to evaluate the efficacy of azelaic acid in the management of acne, rosacea, melasma and skin aging. Pooling randomized controlled trials of at least 6 weeks, it supports topical azelaic acid for reducing inflammatory lesions in rosacea.
    Caution
    Can cause mild stinging, tingling, or dryness at first; introduce gradually and patch-test.
  2. Ferulic Acid (rice bran)

    Supported by smaller clinical studies (Evidence grade B · No traditional record)

    Clinically studied for papulopustular rosacea

    Why it may be relevant
    Ferulic acid has been directly studied in papulopustular rosacea — the type most associated with bumps and pustules — making it especially relevant for this presentation.
    Why try it
    Supported by a randomized controlled study, ferulic acid may help reduce the inflammatory lesions characteristic of papulopustular rosacea.
    Dose or use
    Follow product labeling; consult a healthcare practitioner.
    Time to results
    Typically 4–8 weeks
    Key study
    RCT (2025, PMID 39413013): Ferulic Acid in the Treatment of Papulopustular Rosacea: A Randomized Controlled Study.
    Caution
    For topical use; check formulation compatibility with other active skincare ingredients.
  3. Quercetin

    Not yet assessed· We have not reviewed the literature for this one (Evidence grade not assigned · Traditional use recognised)Recognised traditional use

    Anti-inflammatory flavonoid; not tested alone

    Why it may be relevant
    Quercetin's anti-inflammatory, antioxidant properties make it a plausible fit when rosacea shows bumps and localized skin inflammation.
    Why try it
    Quercetin is a plant flavonoid that may help calm skin inflammation. This use rests on tradition and on its role as one ingredient inside compound formulas, not on trials of quercetin used on its own for rosacea.
    Dose or use
    Follow product labeling; consult a healthcare practitioner.
    Time to results
    Typically 4–8 weeks
    Key study
    Quercetin is a plant flavonoid with antioxidant and anti-inflammatory properties. It has appeared as one ingredient in a multi-component topical rosacea gel (alongside onion extract, heparin sodium, and allantoin), but isolated quercetin has not been tested for rosacea in controlled clinical trials.
    Caution
    For topical use; patch-test first if your skin is highly reactive.

Mostly persistent redness and flushing across my cheeks or nose

  1. Gluconolactone (PHA)

    Limited human trials so far· Most of the research is laboratory or animal work (Evidence grade C · No traditional record)

    Studied for mild rosacea-related redness

    Why it may be relevant
    Gluconolactone has been studied specifically in the context of mild erythema (redness) in rosacea, making it the best match for those whose primary concern is flushing and redness.
    Why try it
    As a polyhydroxy acid (PHA), gluconolactone is a gentle exfoliant that may help improve skin tone and visible redness, with some clinical research supporting its use in mild rosacea-related redness.
    Dose or use
    Follow product labeling; consult a healthcare practitioner.
    Time to results
    Typically 4–8 weeks
    Key study
    Clinical trial (2025, PMID 40111222): Comparison of Efficacy and Willingness to a 5% Gluconolactone-Based Topical Serum and Intense Pulsed Light in Mild Erythema of Rosacea: A Paired Control Study.
    Caution
    PHAs are generally well-tolerated, but patch-test first on sensitive skin.
  2. Green tea extract (topical)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Antioxidant that helps soothe facial redness

    Why it may be relevant
    When redness and flushing dominate, topical green tea's soothing antioxidant action is a gentle fit — the library notes it helps soothe rosacea inflammation.
    Why try it
    Topical green tea extract, rich in EGCG, is antioxidant and anti-inflammatory and can be a gentle way to calm facial redness. It is ungraded here, based on the library's listing rather than an attached trial.
    Dose or use
    Follow product labeling; apply to clean skin. Patch-test first.
    Time to results
    Typically 4-8 weeks
    Key study
    Topical green tea extract from Camellia sinensis has antioxidant and anti-inflammatory properties, and the library lists rosacea ('helps soothe inflammation'). Presented as ungraded — no specific trial is attached here.
    Caution
    Generally well-tolerated; patch-test to rule out sensitivity to the specific formula.
  3. Niacinamide (Nicotinamide)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Vitamin B3 form; calms redness, no flushing

    Why it may be relevant
    For redness-prone skin, niacinamide supports the skin barrier and helps calm redness — and unlike niacin it does not trigger flushing.
    Why try it
    Niacinamide is a form of vitamin B3 that helps reduce redness and strengthen the skin barrier. The library lists rosacea among its uses. It is ungraded here, as no specific trial is attached.
    Dose or use
    Often used as a 2-5% serum or cream; follow product labeling.
    Time to results
    Typically 4-8 weeks
    Key study
    Niacinamide (nicotinamide), a form of vitamin B3, reduces inflammation and supports the skin barrier, and the library lists rosacea among its uses. Unlike niacin it does not cause flushing. Presented as ungraded — no specific trial is attached here.
    Caution
    Well-tolerated by most; very high concentrations can cause mild irritation, so start low.
  4. Topical Caffeine

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Constricts capillaries to ease visible redness

    Why it may be relevant
    When flushing and visible vessels stand out, topical caffeine's vasoconstricting action can help temporarily soften facial redness.
    Why try it
    Topical caffeine narrows small blood vessels, which may reduce the look of facial redness. The library lists facial redness among its uses. It is ungraded here — no specific rosacea trial is attached.
    Dose or use
    Follow product labeling; apply to affected areas. Patch-test first.
    Time to results
    Typically 2-6 weeks
    Key study
    Topical caffeine constricts capillaries and is listed in the library for facial redness and inflammation. Presented as ungraded — no specific rosacea trial is attached here.
    Caution
    For topical use; patch-test on sensitive skin, as some formulas can irritate.

I'd rather work on flare-ups from within, not just what I put on my face

  1. Zinc Deficiency

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Low zinc can worsen inflammatory skin

    Why it may be relevant
    If you are trying to support your skin from within, checking zinc is worthwhile — low zinc can show up as skin rashes and slow healing.
    Why try it
    Zinc supports skin repair and immune regulation, and oral zinc has been explored as an adjunct for rosacea. Correcting a genuine deficiency may help inflammatory skin. Consider testing before supplementing.
    Dose or use
    Ask a practitioner about testing your zinc level before supplementing; do not exceed recommended intakes.
    Time to results
    Varies; weeks to months if a deficiency is corrected
    Key study
    Zinc deficiency can present with skin rashes and impaired healing. Zinc supports skin repair and immune regulation, and oral zinc has been studied as an adjunct for rosacea. Presented as an ungraded from-within angle.
    Caution
    Excess zinc can cause nausea and lead to copper deficiency — supplement only if you are low and under guidance.
  2. LI11 (Quchi) - Large Intestine 11

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Classic point for inflammatory skin conditions

    Why it may be relevant
    If you want to calm flare-ups from within, LI11 is a traditional point used for heat and inflammatory skin conditions.
    Why try it
    LI11 (Quchi), at the outer end of the elbow crease, is used in Traditional Chinese Medicine to clear heat and ease inflammatory skin conditions. This is a traditional practice, not a clinically proven rosacea treatment.
    Dose or use
    Apply firm, steady pressure to the point at the outer elbow crease for 1-2 minutes, a few times a day.
    Time to results
    Varies; used as an ongoing supportive practice
    Key study
    LI11 (Quchi) is a Large Intestine meridian point traditionally used for inflammation and inflammatory skin conditions such as eczema and psoriasis. This is a traditional use, not confirmed by controlled rosacea trials.
    Caution
    Avoid pressing on broken or irritated skin, and avoid strong pressure if pregnant. Not a substitute for medical care.

My skin is so reactive that most products set it off — I need the gentlest options

  1. Green tea extract (topical)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Antioxidant that helps soothe facial redness

    Why it may be relevant
    When redness and flushing dominate, topical green tea's soothing antioxidant action is a gentle fit — the library notes it helps soothe rosacea inflammation.
    Why try it
    Topical green tea extract, rich in EGCG, is antioxidant and anti-inflammatory and can be a gentle way to calm facial redness. It is ungraded here, based on the library's listing rather than an attached trial.
    Dose or use
    Follow product labeling; apply to clean skin. Patch-test first.
    Time to results
    Typically 4-8 weeks
    Key study
    Topical green tea extract from Camellia sinensis has antioxidant and anti-inflammatory properties, and the library lists rosacea ('helps soothe inflammation'). Presented as ungraded — no specific trial is attached here.
    Caution
    Generally well-tolerated; patch-test to rule out sensitivity to the specific formula.
  2. Niacinamide (Nicotinamide)

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Vitamin B3 form; calms redness, no flushing

    Why it may be relevant
    For redness-prone skin, niacinamide supports the skin barrier and helps calm redness — and unlike niacin it does not trigger flushing.
    Why try it
    Niacinamide is a form of vitamin B3 that helps reduce redness and strengthen the skin barrier. The library lists rosacea among its uses. It is ungraded here, as no specific trial is attached.
    Dose or use
    Often used as a 2-5% serum or cream; follow product labeling.
    Time to results
    Typically 4-8 weeks
    Key study
    Niacinamide (nicotinamide), a form of vitamin B3, reduces inflammation and supports the skin barrier, and the library lists rosacea among its uses. Unlike niacin it does not cause flushing. Presented as ungraded — no specific trial is attached here.
    Caution
    Well-tolerated by most; very high concentrations can cause mild irritation, so start low.
  3. LI11 (Quchi) - Large Intestine 11

    Centuries of traditional use· Human evidence not yet assessed (Evidence grade not assigned · Traditional use long-standing)Long-standing traditional staple

    Classic point for inflammatory skin conditions

    Why it may be relevant
    If you want to calm flare-ups from within, LI11 is a traditional point used for heat and inflammatory skin conditions.
    Why try it
    LI11 (Quchi), at the outer end of the elbow crease, is used in Traditional Chinese Medicine to clear heat and ease inflammatory skin conditions. This is a traditional practice, not a clinically proven rosacea treatment.
    Dose or use
    Apply firm, steady pressure to the point at the outer elbow crease for 1-2 minutes, a few times a day.
    Time to results
    Varies; used as an ongoing supportive practice
    Key study
    LI11 (Quchi) is a Large Intestine meridian point traditionally used for inflammation and inflammatory skin conditions such as eczema and psoriasis. This is a traditional use, not confirmed by controlled rosacea trials.
    Caution
    Avoid pressing on broken or irritated skin, and avoid strong pressure if pregnant. Not a substitute for medical care.

Evidence grades describe the strength of published research for Rosacea, not a promise of results. Nothing here is medical advice — talk to your clinician before starting anything, especially alongside prescription medication.

Other ways people describe this

Same underlying problem, different words.

These suggestions come from our full page on Rosacea, where you can see every option and how it is graded. Evidence grades are explained in our methodology, and every phrasing we cover is listed under health topics.

Remedies people try for this

Remedies recommended for the same conditions. Evidence grades are shown on each page.

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Reviewed by the HealisticMD editorial team How we grade evidence →