Educational information, not medical advice — ask your doctor or midwife.
Acidum picricum is a homeopathic remedy. It is made from picric acid, a yellow chemical whose Latin name is trinitrophenol. Homeopaths give it most often for a tired, worn-out mind after long study or worry.
The remedy is made by diluting the source over and over, with hard shaking at each step. At 30C, the usual strength, no molecules of picric acid are left. You are taking a sugar pellet or a drop of water and alcohol.
Trials do not show that this remedy works better than a dummy pill. Its standing rests on long use by homeopaths, not on proof. Traditional use is not the same as proof of effect.
There is no known way for a 30C dilution to act on the body, and that is the honest starting point.
Homeopathy rests on two ideas. The first is "like cures like": a substance that causes symptoms in a well person is said to ease those symptoms in a sick one. The second is that shaking and diluting make a remedy act more strongly, not less.
Chemistry does not back the second idea. Once a liquid is diluted past about 12C, none of the starting material is left in it. A 30C pellet is far past that point.
So any change you feel is best explained in other ways. Time, rest, the care of a practitioner, and the placebo effect (feeling better because you expect to) all play a part.
You will usually find it as small sugar pellets that melt under the tongue.
Common forms are: - Sugar pellets or globules - Soft tablets that dissolve in the mouth - Liquid drops in a water and alcohol base
Common strengths sold to the public are 6C, 12C, 30C and 200C. Higher numbers mean more dilution steps, not more chemical. Very low strengths such as 1X, 2X or 3X may still contain real picric acid and are best avoided.
Picric acid was made in a lab in the 1800s. It was used as a yellow dye and later in explosives and in some old wound dressings.
Homeopaths tested it on healthy people in the late 1800s in the United States and in Europe. Those testers reported deep tiredness, heavy legs and a headache at the back of the head after mental work.
From that, the remedy gained a small but steady place in homeopathic books for what old texts called "brain fag" (mental burn-out) in students and clerks. It has stayed a minor remedy rather than a famous one.
See a doctor if your tiredness lasts more than two weeks, or if it comes with weight loss, fever, night sweats or low mood that will not lift. These can point to a cause that needs testing.
Get help the same day if you have a headache that starts suddenly and hurts badly, weakness on one side of the body, trouble speaking, or numbness that is spreading.
Go to an emergency department if anyone swallows raw picric acid or a very low-strength preparation by mistake. Take the container with you.
Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.
Reviewed by the HealisticMD editorial team How we grade evidence →
The published evidence for Acidum picricum is weak or absent. That usually means no controlled trial has tested it, not that a trial found it ineffective — the two are different, and we grade only what has been published.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
One email with the summary. We'll also send a short weekly evidence update — unsubscribe any time.