Educational information, not medical advice — ask your doctor or midwife.
African mahogany bark is the bark of Khaya senegalensis, a tall tree of the West African savannah. In Hausa the tree is called madaci. The bark is stripped, dried, and usually boiled in water to make a very bitter drink.
In West Africa it has been used for fever and malaria, stomach upsets, worms, and as a bitter tonic. It is also a well known animal remedy, given to cattle and horses. The bark is sold in open markets as chips or powder, often with no label.
Here is the honest verdict on the evidence. There are no good human trials of this bark for any illness. Most of what is known comes from test tubes and from rats and mice.
Long use in a tradition is not proof that something works. It is also not proof that it is safe. That point applies to this whole page, so it is made once here.
The main real-world risk is not exotic. People use the bark for fever instead of getting tested for malaria, and malaria can kill within days.
No one has shown in people how this bark works, or that it works at all.
In test tubes, extracts of the bark slow the growth of Plasmodium falciparum, the parasite that causes the worst malaria. The amounts needed are high. Whether a boiled bark drink reaches those levels in the blood is not known.
In laboratory tests the bark also slows some bacteria and fungi. That is common for bitter, tannin-rich barks. It does not show that it clears an infection in a person.
In rats, bark extracts have lowered blood sugar and reduced some markers of swelling. These are animal findings only. Dose, timing and safety in humans have not been worked out.
The same animal work raises the main worry. At higher doses, rodents given bark extracts showed signs of liver and kidney injury. Blood tests changed, and tissue damage was seen under the microscope.
The bitter taste itself may explain part of the traditional use. Bitter plants can prompt saliva and stomach juices, which some people feel as better appetite. That is a mild, short effect, not a treatment.
The common forms are simple and home-made.
- Bark chips or strips, boiled in water as a decoction - Dried bark powder, stirred into water or pap - Cold water soaks, left to stand overnight - Bark added to mixed herbal blends sold in markets - Alcohol tinctures, mostly outside West Africa - Capsules of bark powder, sold online by small sellers
Market blends are the hardest to judge. They may hold several plants, and the label, if any, rarely lists them. Some blends have been found to contain added drugs.
The tree is also a timber and shade tree. Bark is sometimes taken from trees treated with pesticide or growing beside busy roads.
West African healers have used madaci bark for a long time, across the Sudan and Sahel belt. Written records of it go back to colonial-era plant surveys of the 1800s and 1900s.
Traditional healers used bark decoctions for fever and malaria, jaundice, stomach pain, diarrhoea and worms. Some used it as a bitter tonic for poor appetite. Washes were applied to sores and skin complaints.
It also had a strong place in animal care. Herders gave bark drinks to cattle and horses, including for the wasting disease carried by tsetse flies.
In some communities the bark was used to bring on abortion. That use is recorded in ethnobotany reports, and it shapes the safety advice on this page.
The bark served other trades too. It was used in tanning and dyeing, and the tree gives valued timber. None of this history shows that the bark treats any illness, and none of it is a reason to dose yourself.
Stop and see a doctor the same day if you notice any of these:
- Yellow eyes or yellow skin (jaundice) - Dark urine, or passing much less urine than usual - Pain under your right ribs - Vomiting that will not stop - Severe or bloody diarrhoea
Go to an emergency department now if you have fever with confusion, fits, trouble breathing, or you cannot stay awake. These can be signs of severe malaria.
If you are pregnant and have taken the bark, seek care straight away, even if you feel well.
Tell any doctor you see that you took this bark, and bring the packet or sample.
No regulator has approved African mahogany bark as a medicine. In the United States, the UK and the EU it is not an approved drug, and sellers may not claim it treats disease. In West Africa it is sold freely in markets as a traditional remedy, with little checking of quality. Separately, the whole Khaya group of trees was added to CITES Appendix II in 2022, which controls cross-border trade in its timber.
Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
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