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Borage

Early evidence for: Joint pain in rheumatoid arthritis; Eczema (an itchy skin rash); Premenstrual breast tenderness; Dry skin.

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What is Borage? Borage is a bristly, blue-flowered garden herb, Borago officinalis. German speakers call it Borretsch. Its leaves, flowers and seeds have all been used in European folk practice. Two very different products share the name. Borage seed oil is a supplement rich in a fat called GLA. Borage leaf and flower are used as food, tea or tincture. That split matters for safety. Leaf and flower hold pyrrolizidine alkaloids, natural compounds that can harm the liver. Seed oil sold as a supplement is usually made and tested to be free of them. The evidence verdict is modest. Human trials of borage oil are small and mixed, and the strongest ones are not encouraging. Long traditional use is not proof that borage works, and it is not proof that borage is safe. How does Borage work? If borage seed oil does anything, GLA (gamma-linolenic acid) is the likely reason. Your body turns GLA into signalling fats that help control inflammation, the body's swelling response. In lab and animal studies, those fats appear to damp inflammation down. Small human trials have measured joint tenderness and skin dryness. The results are too patchy to call the effect proven. Folk use of the leaf rested on something simpler. The leaf is full of mucilage, a slippery gel, and was thought to soothe a raw throat and chest. That idea has not been tested in modern trials. The alkaloids in leaf and flower are a hazard, not a benefit. In animals, the liver turns them into reactive products that injure small blood vessels. Repeated exposure is the worry, not one sip. What forms does Borage come in? Most borage sold today is seed oil, in softgel capsules or as a bottled liquid. Labels usually state the GLA content as well as the oil weight. Older forms are still around. Dried leaf is sold as tea. Fresh young leaves are eaten as a vegetable in parts of Europe. Flowers decorate salads and summer drinks. Tincture, an alcohol extract of the leaf, turns up in herb shops. Cold-pressed borage oil also appears in skin creams and lotions. The form drives the risk. Leaf and flower products can carry the liver-toxic alkaloids. Seed oil pressed from cleaned seed usually does not, if the maker tests for it. If you buy seed oil, look for a clear PA-free claim on the pack. Borage oil also goes rancid easily. Keep it cool and watch the date. Where it comes from: Borage has a long record in European folk practice. Medieval herbalists tied it to courage and good cheer. An old Latin tag ran: I, borage, bring always courage. Sixteenth-century writers such as John Gerard listed it for melancholy, fever and sore throat. Country use put the leaf into soups, salads and wine cordials. German tradition knows it as Borretsch. Its cucumber-flavoured leaves are a classic part of Frankfurt green sauce. Seed oil is a modern product, born of twentieth-century interest in GLA. These records show what people did, not what worked. Chemists later found the liver-toxic alkaloids that older users had no way to see.

Helps

What does Borage help with? Joint pain and stiffness in rheumatoid arthritis: This is the best-studied use of borage seed oil. A few small trials found less joint tenderness and swelling after several months of GLA. The trials were small and most were funded or short. Reviewers rate the evidence as weak and not enough to recommend borage as a treatment. It is not a replacement for arthritis medicines. Talk to your rheumatologist before adding it. Eczema (atopic dermatitis, an itchy skin rash): Here the evidence is fairly clear, and it is negative. Borage oil was once a popular eczema supplement. A Cochrane review pooled trials of oral borage and evening primrose oil. It found no meaningful benefit for eczema symptoms over placebo. Some small studies of oil applied to the skin report mild softening. That is a moisturiser effect, not a cure for the condition. Premenstrual symptoms and breast tenderness: GLA oils have long been promoted for cyclical breast pain. Most of that research used evening primrose oil rather than borage. The better trials show little or no benefit over placebo. Evidence for borage itself is very thin. If breast pain is new, one-sided or comes with a lump, get it checked rather than self-treating. Dry, rough or ageing skin: Borage oil is a common ingredient in skin creams. Applied to skin, it acts as an emollient and softens the surface. A few small studies suggest oral GLA may reduce water loss through the skin. The effect is modest and not consistently found. Any plain moisturiser does much the same job for less money. Coughs and sore throat (traditional use only): Folk healers gave borage leaf tea for chesty coughs and raw throats. The slippery mucilage was thought to coat and soothe. There are no modern human trials supporting this. Leaf tea is also the form that carries the liver-toxic alkaloids. For a sore throat, safer soothing options exist. Ask a pharmacist. Low mood and 'melancholy' (traditional use only): Old European texts called borage a cheering herb. It was added to wine to lift the spirits. No human trial supports borage for low mood or anxiety. The claim is cultural, not medical. If your mood has been low for weeks, speak to a doctor.

Borage

Quick Facts

  • What it is: A blue-flowered European herb whose seed yields an oil rich in GLA, while its leaf and flower carry liver-toxic alkaloids.
  • Main uses: Joint pain in rheumatoid arthritis, Eczema (an itchy skin rash), Premenstrual breast tenderness, Dry skin
  • Active ingredients: GLA (gamma-linolenic acid), Linoleic acid, Oleic acid, Mucilage, Pyrrolizidine alkaloids (amabiline, lycopsamine, intermedine)
  • Forms: Seed oil softgel capsules, Bottled seed oil, Skin creams and lotions, Dried leaf tea, Tincture (alcohol extract), Fresh leaves and flowers as food
  • Time to effect: Weeks, if at all; six weeks or more in trials
  • Side effects: Mild gut upset and burping from the oil; leaf and tea can damage the liver.
  • Pregnancy & breastfeeding: Avoid in pregnancy and while breastfeeding.

Educational information, not medical advice — ask your doctor or midwife.

What is Borage?

Borage is a bristly, blue-flowered garden herb, Borago officinalis. German speakers call it Borretsch. Its leaves, flowers and seeds have all been used in European folk practice.

Two very different products share the name. Borage seed oil is a supplement rich in a fat called GLA. Borage leaf and flower are used as food, tea or tincture.

That split matters for safety. Leaf and flower hold pyrrolizidine alkaloids, natural compounds that can harm the liver. Seed oil sold as a supplement is usually made and tested to be free of them.

The evidence verdict is modest. Human trials of borage oil are small and mixed, and the strongest ones are not encouraging. Long traditional use is not proof that borage works, and it is not proof that borage is safe.

How does Borage work?

If borage seed oil does anything, GLA (gamma-linolenic acid) is the likely reason. Your body turns GLA into signalling fats that help control inflammation, the body's swelling response.

In lab and animal studies, those fats appear to damp inflammation down. Small human trials have measured joint tenderness and skin dryness. The results are too patchy to call the effect proven.

Folk use of the leaf rested on something simpler. The leaf is full of mucilage, a slippery gel, and was thought to soothe a raw throat and chest. That idea has not been tested in modern trials.

The alkaloids in leaf and flower are a hazard, not a benefit. In animals, the liver turns them into reactive products that injure small blood vessels. Repeated exposure is the worry, not one sip.

What forms does Borage come in?

Most borage sold today is seed oil, in softgel capsules or as a bottled liquid. Labels usually state the GLA content as well as the oil weight.

Older forms are still around. Dried leaf is sold as tea. Fresh young leaves are eaten as a vegetable in parts of Europe.

Flowers decorate salads and summer drinks. Tincture, an alcohol extract of the leaf, turns up in herb shops. Cold-pressed borage oil also appears in skin creams and lotions.

The form drives the risk. Leaf and flower products can carry the liver-toxic alkaloids. Seed oil pressed from cleaned seed usually does not, if the maker tests for it.

If you buy seed oil, look for a clear PA-free claim on the pack. Borage oil also goes rancid easily. Keep it cool and watch the date.

Where it comes from:

Borage has a long record in European folk practice. Medieval herbalists tied it to courage and good cheer. An old Latin tag ran: I, borage, bring always courage.

Sixteenth-century writers such as John Gerard listed it for melancholy, fever and sore throat. Country use put the leaf into soups, salads and wine cordials.

German tradition knows it as Borretsch. Its cucumber-flavoured leaves are a classic part of Frankfurt green sauce. Seed oil is a modern product, born of twentieth-century interest in GLA.

These records show what people did, not what worked. Chemists later found the liver-toxic alkaloids that older users had no way to see.

Who should avoid Borage?

  • Do not drink borage leaf tea or take borage leaf or flower products if you are pregnant or breastfeeding; the alkaloids can reach the baby.
  • Never give borage leaf, flower or tea to babies or young children.
  • Do not use any borage product if you have liver disease, such as hepatitis or cirrhosis (scarring of the liver).
  • Do not combine borage leaf or tea with heavy drinking or with liver-stressing drugs such as methotrexate or isoniazid.
  • Do not use borage products that are not labelled free of pyrrolizidine alkaloids.
  • Do not take borage oil if you have a bleeding disorder, such as haemophilia.
  • Do not take borage oil alongside warfarin, clopidogrel or other blood thinners unless your doctor agrees.
  • Avoid borage oil in the two weeks before planned surgery.
  • Do not use borage oil if you have epilepsy (a seizure disorder) or take phenothiazine drugs such as chlorpromazine.
  • Do not use borage if you are allergic to it or to other plants in the borage family, such as comfrey.

When should you see a doctor?

Stop taking borage and get medical help if you notice:

Yellow skin or eyes (jaundice), dark urine, or pale stools.

Pain or swelling in the upper right side of your belly, or a belly that swells up quickly.

Lasting nausea, vomiting or deep tiredness with no clear cause.

Unusual bruising, nosebleeds, bleeding gums or black stools.

A seizure, or any sudden blackout. Call emergency services for this.

Tell the doctor exactly which borage product you took and for how long. Bring the pack if you can.

Is Borage legal where you live?

In the UK, EU and US, borage seed oil is sold as an ordinary food supplement. It is not approved as a medicine for any disease.

EU rules set strict limits on pyrrolizidine alkaloids in herbal teas and supplements, and German authorities have long restricted borage leaf products.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

Reviewed by the HealisticMD editorial team How we grade evidence →

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