Educational information, not medical advice.See how evidence is graded

Centella asiatica

Traditionally used for: Memory and focus; Wound and scar healing; Anxiety and stress; Vein and circulation health; Skin firmness.

Home

What is centella asiatica? Centella asiatica, also known as Gotu Kola, is a perennial herb commonly used in traditional medicine practices in Asia, Africa, and India. It has been used for centuries for its medicinal properties, and recent studies have shown that it may have potential health benefits. How does it work? Centella asiatica contains several active ingredients, including triterpenoids, asiaticoside, madecassoside, and asiatic acid, which are responsible for its medicinal properties. These compounds have been shown to have anti-inflammatory, antioxidant, and neuroprotective effects, which may help improve cognitive function, reduce anxiety and depression, and improve wound healing. What are the active ingredients that are important for its medicinal properties? The active ingredients that are important for Centella asiatica's medicinal properties include triterpenoids, asiaticoside, madecassoside, and asiatic acid. What forms does it come in? Centella asiatica is available in various forms, including capsules, tablets, powders, and extracts. When was it first used for medicinal purposes? Centella asiatica has been used for medicinal purposes for centuries in traditional medicine practices in Asia, Africa, and India.

Helps

What does Centella asiatica help with? Memory and focus: Gotu Kola has a centuries-long reputation as a brain tonic, and modern research backs it up. Its active compounds appear to protect neurons, support healthy blood flow to the brain, and boost acetylcholine — a key chemical for learning and recall. Regular use over 4–8 weeks has been associated with measurable improvements in memory, attention, and mental processing speed. Anxiety and stress: Several small clinical trials have found that Gotu Kola reduces anxiety and startle responses without causing sedation. It appears to calm overactive stress signaling in the brain, making it a gentle option for everyday anxiety, nervousness, or mild situational stress. Wound healing and scars: Asiaticoside and madecassoside actively stimulate collagen synthesis and skin cell regeneration, making Gotu Kola one of the better-studied natural wound healers. Both topical and oral forms have been shown in clinical studies to speed up wound closure and reduce scar formation — it is even used as a pharmaceutical-grade ingredient in professional wound care products. Stretch marks: Centella asiatica is one of the few natural ingredients with clinical trial evidence for stretch mark prevention and reduction. Its collagen-boosting triterpenoids help strengthen the skin's connective tissue layer, and studies on pregnant women have shown it reduces new stretch mark formation when applied consistently. Skin firmness and aging: By stimulating fibroblasts — the skin cells responsible for making collagen and elastin — Gotu Kola helps firm and thicken skin that has thinned with age. It is widely used in dermatology-grade skincare for this reason, and trials have documented visible improvements in skin elasticity with regular topical use. Chronic venous insufficiency and leg swelling: This is one of the most clinically supported uses of Centella asiatica. Multiple controlled trials in Europe, where it has been used as a registered medicine, show that standardized Gotu Kola extracts significantly reduce leg heaviness, swelling, pain, and nighttime cramping associated with poor vein function. Sleep quality: Its calming effect on the nervous system can ease the mental restlessness that delays sleep. Some users report better sleep onset and reduced nighttime waking, likely related to its anxiety-lowering and mild adaptogenic properties rather than direct sedation. Peripheral neuropathy: Early clinical evidence suggests Gotu Kola may support nerve fiber regeneration and reduce the tingling, numbness, and pain of peripheral neuropathy — particularly in diabetic patients. This may be related to both its neuroprotective compounds and its ability to improve microcirculation to nerve tissue. Psoriasis and eczema (topical): Topical Centella asiatica preparations have shown promise for reducing redness, itching, and scaling in inflammatory skin conditions. Its anti-inflammatory triterpenes help calm skin barrier dysfunction, and it is increasingly found in dermatologist-recommended barrier repair formulas.

Centella asiatica

Quick Facts

  • What it is: A creeping herb native to Asia used for thousands of years to support brain function, wound healing, and circulation.
  • Main uses: Sharpens memory and focus, speeds wound and scar healing, calms anxiety, and supports healthy veins and skin.
  • Best for: Memory and focus, Wound and scar healing, Anxiety and stress, Vein and circulation health, Skin firmness
  • Active ingredients: Asiaticoside, Madecassoside, Asiatic acid, Madecassic acid, Brahmoside, Quercetin, Kaempferol
  • Forms: Capsule, Standardized extract, Tincture, Topical cream/gel, Fresh leaf, Powder, Tea
  • Time to effect: Skin and wound benefits in 2–4 weeks; cognitive and anxiety effects in 4–8 weeks of consistent use.
  • Side effects: Generally well-tolerated; mild stomach upset and rare skin reactions have been reported, and it should be avoided during pregnancy.
  • Pregnancy & breastfeeding: Not assessed for this entry. Ask your doctor or midwife before use.

Educational information, not medical advice — ask your doctor or midwife.

What is centella asiatica?

Centella asiatica, also known as Gotu Kola, is a perennial herb commonly used in traditional medicine practices in Asia, Africa, and India. It has been used for centuries for its medicinal properties, and recent studies have shown that it may have potential health benefits.

How does it work?

Centella asiatica contains several active ingredients, including triterpenoids, asiaticoside, madecassoside, and asiatic acid, which are responsible for its medicinal properties. These compounds have been shown to have anti-inflammatory, antioxidant, and neuroprotective effects, which may help improve cognitive function, reduce anxiety and depression, and improve wound healing.

What are the active ingredients that are important for its medicinal properties?

The active ingredients that are important for Centella asiatica's medicinal properties include triterpenoids, asiaticoside, madecassoside, and asiatic acid.

What forms does it come in?

Centella asiatica is available in various forms, including capsules, tablets, powders, and extracts.

When was it first used for medicinal purposes?

Centella asiatica has been used for medicinal purposes for centuries in traditional medicine practices in Asia, Africa, and India.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

Reviewed by the HealisticMD editorial team How we grade evidence →

Remedies related to Centella asiatica

People take Centella asiatica when they say

Everyday descriptions of the problems this remedy is recommended for.

Conditions where Centella asiatica is recommended

Each grade below is for that condition specifically, not for Centella asiatica in general.

Natural options for Anti-aging, ranked by evidence

The 5 options with the best evidence for Anti-aging, each with its grade and who should avoid it. One email.

Occasional evidence updates after that — unsubscribe any time.