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Chi Shao

Traditionally used for: Blood circulation and stagnation; Liver inflammation; Menstrual pain and irregularity. Primarily used to improve blood circulation.

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What is Chi Shao? Chi Shao, or Red Peony Root, comes from the root of Paeonia lactiflora or Paeonia veitchii and has been a cornerstone of Traditional Chinese Medicine for over 2,000 years . It is classified as a blood-moving herb, meaning it is used to break up sluggish circulation, relieve pain, and clear heat from the blood. Unlike its close relative Bai Shao (White Peony Root), Chi Shao is less processed and retains a stronger action on blood stagnation and inflammation. How does Chi Shao work? Chi Shao works mainly through its key compound paeoniflorin, which has well-documented anti-inflammatory, antiplatelet, and antioxidant properties. It appears to reduce the tendency of blood to clump and clot, improve microcirculation, and calm overactive immune and inflammatory responses. It also supports liver function by protecting liver cells from oxidative stress and reducing liver inflammation. What forms does Chi Shao come in? In traditional practice, Chi Shao is most often prepared as a decoction (boiled in water) alongside other herbs. Modern supplements are available as standardized capsules or liquid extracts, often standardized to paeoniflorin content. Powder form can be used in smoothies or encapsulated for convenience. Where it comes from: Chi Shao appears in some of the oldest classical Chinese medical texts, including the Shennong Bencao Jing (Divine Farmer's Materia Medica), and has been used continuously for over two millennia. It is a key ingredient in classical formulas like Xue Fu Zhu Yu Tang (Drive Out Stasis in the Mansion of Blood) and Tao Hong Si Wu Tang, both of which are still commonly prescribed today for cardiovascular and gynecological conditions.

Helps

What does Chi Shao help with? Poor circulation and blood stagnation: Chi Shao is considered one of TCM's premier herbs for moving stuck blood. Its active compounds reduce platelet clumping and improve blood flow through small vessels, which can help with conditions ranging from bruising to chronic pain linked to sluggish circulation. Liver inflammation and liver disease: Chi Shao has been studied extensively in China for liver conditions, particularly viral hepatitis and early liver fibrosis. It helps reduce liver inflammation, supports the breakdown of scar tissue, and protects liver cells from oxidative damage. Menstrual pain and irregularity: In TCM, painful or irregular periods are often attributed to blood stagnation. Chi Shao is commonly used in formulas to relax uterine muscle tension, reduce cramping, and regulate the menstrual cycle by improving pelvic blood flow. Dysmenorrhea (painful periods): Several Chinese clinical trials have used Chi Shao-containing formulas specifically for dysmenorrhea, finding reduced pain intensity and duration. The herb's antispasmodic and blood-moving actions work together to ease uterine cramping. Inflammatory skin conditions: Chi Shao is used both internally and occasionally topically for skin conditions linked to heat and inflammation, such as acne, rosacea, and eczema. Its ability to cool blood heat and reduce inflammatory signaling makes it a useful support for reactive skin. Cardiovascular health: Paeoniflorin in Chi Shao has been shown to reduce platelet aggregation and support healthy blood vessel function. This makes Chi Shao a common ingredient in TCM formulas aimed at reducing cardiovascular risk in people with signs of blood stagnation. Abdominal and pelvic pain: Chi Shao is frequently combined with other herbs for dull, fixed pain in the abdomen or pelvis — a classic sign of blood stagnation in TCM. The antispasmodic and circulation-improving properties help relieve this type of chronic, congestion-related pain. Early-stage liver fibrosis: Research from Chinese hospitals suggests Chi Shao, particularly in formula combinations, may help slow the progression of liver fibrosis by reducing stellate cell activation and collagen buildup. It is often used as an adjunct to conventional hepatitis treatment in Chinese integrative medicine. Chronic inflammatory conditions: Because paeoniflorin broadly dials down inflammatory signaling, Chi Shao is used as a supporting herb in formulas for a range of chronic inflammatory conditions, including inflammatory joint pain and autoimmune-related heat symptoms.

Quick Facts

  • What it is: Chi Shao is the dried root of red peony, one of the most widely used herbs in Traditional Chinese Medicine for moving blood and clearing heat.
  • Main uses: Primarily used to improve blood circulation, reduce inflammation, support liver health, and ease pain caused by blood stagnation.
  • Best for: Blood circulation and stagnation, Liver inflammation, Menstrual pain and irregularity
  • Active ingredients: Paeoniflorin, Pentagalloylglucose, Gallic acid, Albiflorin, Oxypaeoniflorin, Benzoic acid
  • Forms: Dried root (decoction), Powder, Capsule, Liquid extract, Traditional herbal formula
  • Time to effect: Acute effects on circulation may begin within days; benefits for chronic inflammatory or liver conditions typically take 4–8 weeks of consistent use.
  • Side effects: Generally well tolerated at standard doses, but may cause mild stomach upset and should be used cautiously with blood-thinning medications.
  • Pregnancy & breastfeeding: Not assessed for this entry. Ask your doctor or midwife before use.

Educational information, not medical advice — ask your doctor or midwife.

What is Chi Shao?

Chi Shao, or Red Peony Root, comes from the root of Paeonia lactiflora or Paeonia veitchii and has been a cornerstone of Traditional Chinese Medicine for over 2,000 years. It is classified as a blood-moving herb, meaning it is used to break up sluggish circulation, relieve pain, and clear heat from the blood. Unlike its close relative Bai Shao (White Peony Root), Chi Shao is less processed and retains a stronger action on blood stagnation and inflammation.

How does Chi Shao work?

Chi Shao works mainly through its key compound paeoniflorin, which has well-documented anti-inflammatory, antiplatelet, and antioxidant properties. It appears to reduce the tendency of blood to clump and clot, improve microcirculation, and calm overactive immune and inflammatory responses. It also supports liver function by protecting liver cells from oxidative stress and reducing liver inflammation.

What forms does Chi Shao come in?

In traditional practice, Chi Shao is most often prepared as a decoction (boiled in water) alongside other herbs. Modern supplements are available as standardized capsules or liquid extracts, often standardized to paeoniflorin content. Powder form can be used in smoothies or encapsulated for convenience.

Where it comes from:

Chi Shao appears in some of the oldest classical Chinese medical texts, including the Shennong Bencao Jing (Divine Farmer's Materia Medica), and has been used continuously for over two millennia. It is a key ingredient in classical formulas like Xue Fu Zhu Yu Tang (Drive Out Stasis in the Mansion of Blood) and Tao Hong Si Wu Tang, both of which are still commonly prescribed today for cardiovascular and gynecological conditions.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

Reviewed by the HealisticMD editorial team How we grade evidence →

The published evidence for Chi Shao is weak or absent. That usually means no controlled trial has tested it, not that a trial found it ineffective — the two are different, and we grade only what has been published.

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