Educational information, not medical advice — ask your doctor or midwife.
Chi Shao, or Red Peony Root, comes from the root of Paeonia lactiflora or Paeonia veitchii and has been a cornerstone of Traditional Chinese Medicine for over 2,000 years. It is classified as a blood-moving herb, meaning it is used to break up sluggish circulation, relieve pain, and clear heat from the blood. Unlike its close relative Bai Shao (White Peony Root), Chi Shao is less processed and retains a stronger action on blood stagnation and inflammation.
Chi Shao works mainly through its key compound paeoniflorin, which has well-documented anti-inflammatory, antiplatelet, and antioxidant properties. It appears to reduce the tendency of blood to clump and clot, improve microcirculation, and calm overactive immune and inflammatory responses. It also supports liver function by protecting liver cells from oxidative stress and reducing liver inflammation.
In traditional practice, Chi Shao is most often prepared as a decoction (boiled in water) alongside other herbs. Modern supplements are available as standardized capsules or liquid extracts, often standardized to paeoniflorin content. Powder form can be used in smoothies or encapsulated for convenience.
Chi Shao appears in some of the oldest classical Chinese medical texts, including the Shennong Bencao Jing (Divine Farmer's Materia Medica), and has been used continuously for over two millennia. It is a key ingredient in classical formulas like Xue Fu Zhu Yu Tang (Drive Out Stasis in the Mansion of Blood) and Tao Hong Si Wu Tang, both of which are still commonly prescribed today for cardiovascular and gynecological conditions.
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Reviewed by the HealisticMD editorial team How we grade evidence →
The published evidence for Chi Shao is weak or absent. That usually means no controlled trial has tested it, not that a trial found it ineffective — the two are different, and we grade only what has been published.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
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