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Henna (Lawsonia inermis) is a small flowering shrub native to North Africa, the Middle East, South Asia, and parts of Southeast Asia, cultivated for at least 5,000 years. Its leaves are dried and ground into a fine powder that releases lawsone, a reddish-orange dye molecule with documented antimicrobial and anti-inflammatory properties. Beyond its iconic use as a body art dye, henna has a rich history in Ayurvedic, Unani, and traditional Arabic medicine as a therapeutic plant.
Lawsone, the primary active compound, binds to keratin proteins in hair and skin, which explains both its staining and conditioning effects on hair strands. It also disrupts microbial cell membranes, giving henna its antifungal and antibacterial action. The tannins and gallic acid in the leaf provide astringent and anti-inflammatory effects that help calm irritated skin and support wound healing.
Leaf powder mixed into a paste is the classic and most widely used form — applied topically to hair, scalp, or skin. Oil infusions are used for scalp massage and hair conditioning. Traditional medicine systems also used leaf decoctions orally for fever, liver support, and infection, though oral use requires careful dosing. Standardized capsules and extracts exist but are far less common than topical applications.
Henna has been used for over 5,000 years across Egypt, Persia, India, and North Africa — documented in ancient Ayurvedic texts, Unani medicine, and Islamic prophetic medicine (Tibb al-Nabawi). It has been used to cool the body in desert heat, condition hair, decorate skin for rituals and celebrations, and treat skin infections and wounds. Its cross-cultural footprint is one of the broadest of any medicinal plant.
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