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Khamira Marwareed is a classical Unani compound formulation — a richly aromatic, honey-based electuary whose star ingredient is finely processed pearl powder, combined with precious botanicals like saffron, sandalwood, rose, amber, and gold and silver leaf. It has been a cornerstone cardiac and neurological tonic in the Unani Tibb (Greco-Islamic medicine) tradition for well over a thousand years, documented in foundational texts by Ibn Sina (Avicenna) and later standardized in the National Formulary of Unani Medicine (NFUM) in South Asia. The formulation is designed to simultaneously nourish the heart muscle, calm the nervous system, and sharpen mental clarity.
In Unani philosophy, Khamira Marwareed works by strengthening the Rooh (vital spirit) seated in the heart and by balancing the temperament (Mizaj) of the cardiac and cerebral organs. From a modern perspective, several of its ingredients have demonstrated measurable effects: pearl powder provides bioavailable calcium and trace minerals that support cardiac conduction; saffron's active compounds (crocin, safranal) have documented antidepressant and antioxidant activity; sandalwood and rose have calming, anxiolytic properties; and camphor in small amounts acts as a mild cardiac stimulant and circulatory aid. The combined synergy of these ingredients is thought to reduce oxidative stress in cardiac tissue, regulate autonomic nervous system tone, and support neurotransmitter balance.
Khamira Marwareed is traditionally dispensed as a thick, fragrant electuary paste consumed directly from a spoon or dissolved in warm water or milk. It is commercially manufactured and sold in jars by licensed Unani pharmacies, particularly in India, Pakistan, and Bangladesh, under government-regulated Unani formulary standards. It is not commonly available as capsules or tablets, as the electuary form is considered essential to both palatability and therapeutic delivery in the Unani tradition.
Khamira Marwareed traces its roots to classical Greco-Islamic medicine, with early references in Ibn Sina's 11th-century Canon of Medicine (Al-Qanun fi al-Tibb), where pearl-based cardiac formulations were prescribed for heart weakness, palpitations, and melancholy. The formulation was further refined by later Unani physicians like Ibn Baytar and Al-Biruni and became a standard preparation in Mughal-era royal pharmacopeias. Today it remains officially recognized in India's National Formulary of Unani Medicine and is manufactured by regulated Unani pharmaceutical companies.
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Reviewed by the HealisticMD editorial team How we grade evidence →
The published evidence for Khamira Marwareed (Unani) is weak or absent. That usually means no controlled trial has tested it, not that a trial found it ineffective — the two are different, and we grade only what has been published.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
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