Educational information, not medical advice.See how evidence is graded

Krill Phospholipids

Best studied for: Cardiovascular health; PMS and hormonal mood swings; Brain health and cognitive support. Supports heart health, brain function.

Home

What is Krill Phospholipids? Krill phospholipids are omega-3 fats extracted from Antarctic krill and packaged in a phospholipid structure — the same form your cell membranes are made of. This makes them uniquely easy for the body to absorb and put to work compared to the triglyceride form found in most fish oils. They also come naturally bundled with astaxanthin, a potent antioxidant that protects the delicate omega-3 fats from going rancid inside your body. How does Krill Phospholipids work? Because the EPA and DHA in krill are attached to phospholipids rather than triglycerides, they're transported directly into cells much more efficiently — studies suggest you need a smaller dose to reach the same blood levels as standard fish oil. The phospholipid carrier also doubles as a building block for cell membranes, supporting brain cell signaling, reducing inflammatory messengers, and helping the liver manage fat and cholesterol metabolism. Astaxanthin works alongside, protecting tissues from oxidative damage. What forms does Krill Phospholipids come in? Softgel and hard-shell capsules are the most common forms and protect the oils from oxidation. Liquid krill oil exists but is less shelf-stable. Most clinical research has used encapsulated krill oil products standardized to a specific phospholipid and astaxanthin content. Look for products that list total phospholipid content (ideally 40% +) alongside EPA and DHA amounts. Where it comes from: Krill have been harvested as food in Japan (called okiami) and by fishing communities in Norway and Russia for generations. The targeted extraction of phospholipid-rich oil as a supplement is a product of the past 25–30 years , driven by research into superior omega-3 bioavailability. The Antarctic krill fishery is today one of the most tightly regulated in the world, making krill oil among the more sustainably sourced marine supplements available.

Helps

What does Krill Phospholipids help with? High triglycerides and cholesterol: Krill phospholipids help lower triglycerides and modestly raise HDL (good) cholesterol through their EPA and DHA content. The phospholipid delivery form appears to support these effects at lower doses than conventional fish oil, with additional liver-level benefits from the choline content. PMS and period-related mood and pain: This is one of krill oil's most well-studied benefits. Women taking krill oil during their cycle report meaningful reductions in cramps, bloating, breast tenderness, and mood swings. The anti-inflammatory omega-3s help dial down the prostaglandins responsible for menstrual cramping. Joint pain and inflammation: Krill phospholipids reduce key inflammatory markers in the body, and people with mild to moderate knee and joint discomfort often notice less stiffness and easier movement after consistent use. The effect is thought to come from omega-3s competing with inflammatory fats in joint tissue. Brain health and memory: DHA is the primary structural fat in the brain, and the phospholipid form in krill oil crosses into brain tissue particularly well. The phosphatidylserine content adds further support for memory, focus, and mental sharpness, especially as we age. Dry eyes: Omega-3s — especially in the phospholipid form — help support the oily layer of the tear film, reducing evaporation and relieving the gritty, burning feeling of dry eyes. Some eye health trials have specifically noted benefit from krill oil over fish oil in this area. Liver fat (non-alcoholic fatty liver): The choline in krill phospholipids plays a direct role in helping the liver package and export fat, reducing accumulation. Early research in people with high liver fat shows krill phospholipids may outperform regular fish oil for this specific concern. Inflammation and oxidative stress: The combination of anti-inflammatory EPA/DHA and the powerful antioxidant astaxanthin gives krill oil a dual action — it reduces inflammatory signaling while protecting cells from oxidative damage. C-reactive protein (CRP), a key inflammation marker, has been shown to drop with krill oil use. Low omega-3 status: People with a low omega-3 index — common in Western diets — can raise their blood omega-3 levels effectively with krill phospholipids, often using a smaller daily dose than equivalent fish oil products due to the superior absorption of the phospholipid form. Perimenopause symptoms: Emerging research and clinical observation suggest krill oil may ease some hormonal transition symptoms including mood variability, joint aches, and cognitive fog, likely through its combined anti-inflammatory and brain-supportive actions. ADHD-related attention difficulties (children and adults): Omega-3s are among the most studied natural supports for attention and focus. Krill oil's phospholipid-DHA form may be especially relevant given how directly it reaches brain tissue, and preliminary studies show modest improvements in attention and hyperactivity scores.

Krill Phospholipids

Quick Facts

  • What it is: A concentrated extract from tiny Antarctic shrimp-like crustaceans that delivers omega-3 fatty acids in a phospholipid form your body absorbs more readily than regular fish oil.
  • Main uses: Supports heart health, brain function, joint comfort, and hormonal balance — especially in women during PMS and perimenopause.
  • Best for: Cardiovascular health, PMS and hormonal mood swings, Brain health and cognitive support
  • Active ingredients: Phosphatidylcholine-bound EPA (eicosapentaenoic acid), Phosphatidylcholine-bound DHA (docosahexaenoic acid), Phosphatidylcholine (PC), Phosphatidylserine (PS), Astaxanthin, Sphingomyelin, Lysophosphatidylcholine (LPC)
  • Forms: Softgel capsule, Hard-shell capsule, Liquid krill oil
  • Time to effect: 4–8 weeks for most benefits; joint and mood effects sometimes noticed sooner (2–4 weeks)
  • Side effects: Generally very well tolerated — occasional mild fishy aftertaste, nausea, or loose stools, particularly at higher doses.
  • Pregnancy & breastfeeding: Not assessed for this entry. Ask your doctor or midwife before use.

Educational information, not medical advice — ask your doctor or midwife.

What is Krill Phospholipids?

Krill phospholipids are omega-3 fats extracted from Antarctic krill and packaged in a phospholipid structure — the same form your cell membranes are made of. This makes them uniquely easy for the body to absorb and put to work compared to the triglyceride form found in most fish oils. They also come naturally bundled with astaxanthin, a potent antioxidant that protects the delicate omega-3 fats from going rancid inside your body.

How does Krill Phospholipids work?

Because the EPA and DHA in krill are attached to phospholipids rather than triglycerides, they're transported directly into cells much more efficiently — studies suggest you need a smaller dose to reach the same blood levels as standard fish oil. The phospholipid carrier also doubles as a building block for cell membranes, supporting brain cell signaling, reducing inflammatory messengers, and helping the liver manage fat and cholesterol metabolism. Astaxanthin works alongside, protecting tissues from oxidative damage.

What forms does Krill Phospholipids come in?

Softgel and hard-shell capsules are the most common forms and protect the oils from oxidation. Liquid krill oil exists but is less shelf-stable. Most clinical research has used encapsulated krill oil products standardized to a specific phospholipid and astaxanthin content. Look for products that list total phospholipid content (ideally 40%+) alongside EPA and DHA amounts.

Where it comes from:

Krill have been harvested as food in Japan (called okiami) and by fishing communities in Norway and Russia for generations. The targeted extraction of phospholipid-rich oil as a supplement is a product of the past 25–30 years, driven by research into superior omega-3 bioavailability. The Antarctic krill fishery is today one of the most tightly regulated in the world, making krill oil among the more sustainably sourced marine supplements available.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

Reviewed by the HealisticMD editorial team How we grade evidence →

Remedies related to Krill Phospholipids

The evidence behind this remedy, in one page

What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.

One email with the summary. We'll also send a short weekly evidence update — unsubscribe any time.