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Liquorice

Early evidence for: Indigestion; Sore throat and dry cough; Mouth ulcers; Heartburn.

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What is Liquorice? Liquorice is the root of Glycyrrhiza glabra, a small legume shrub. In German it is called Süßholz, meaning "sweet wood". The dried root and its extracts go into sweets, teas, cough syrups and capsules. European folk healers reached for it mainly for coughs, sore throats and upset stomachs. Long use in a tradition is not proof that a remedy works. It is also not proof that it is safe. Honest verdict: human evidence for benefit is thin and comes from a few small trials. The harm side is better proven than the benefit side. Glycyrrhizin, the sweet compound in the root, can raise blood pressure and drop potassium (a key body salt). That effect is well documented in people, and it is dose related. How does Liquorice work? The best-proven action of liquorice in people is on salt and water balance, and it is not a wanted one. The gut turns glycyrrhizin into glycyrrhetinic acid. In people, this blocks a kidney enzyme (a helper protein) that normally switches off cortisol, a stress hormone. The body then holds sodium and water and loses potassium. This is why blood pressure can rise, ankles can swell and muscles can weaken. The effect builds with daily use. The soothing claims are less certain. In test tubes and animal work, liquorice compounds appear to calm inflammation and coat irritated tissue. In lab tests, some compounds slow Helicobacter pylori, a stomach bug linked to ulcers. Whether that happens inside a person's stomach is not established. DGL stands for deglycyrrhizinated liquorice, which has most glycyrrhizin stripped out. The idea is to keep the soothing feel without the blood pressure risk. Human proof that DGL helps ulcers or indigestion is limited and mostly old. What forms does Liquorice come in? The key question with any form is how much glycyrrhizin it carries, and that varies hugely. Dried root pieces and root powder are brewed as tea or chewed. Teabags and cut-root blends appear in many cough and stomach teas, often mixed with other herbs. Liquid extracts and tinctures are concentrated. Strength differs from maker to maker. Capsules and tablets often state a glycyrrhizin amount on the label. That number is worth reading. DGL chewable tablets have most of the glycyrrhizin removed. They are sold for stomach complaints. Liquorice sweets and salty liquorice count too. So do some pastis-style drinks, herbal cough syrups and chewing tobaccos. People often forget these add up. Gels and creams with glabridin are sold for skin tone. Human evidence for that use is weak. Where it comes from: Liquorice has one of the longest records of any European herb. Greek and Roman writers described the sweet root, and it later filled monastery gardens. In German-speaking lands it was known as Süßholz. Bamberg in Bavaria grew it on a large scale for centuries. Folk use centred on dry coughs, hoarseness, sore throats and sour stomachs. It was boiled into black sticks, syrups and lozenges. Apothecaries also used it to mask the taste of bitter medicines. That habit carried into modern pharmacy. From the 1900s it became a sweet as much as a medicine, especially in the Netherlands and the Nordic countries. Its salt and water effect was only described by doctors in the mid-20th century, after cases of swelling and high blood pressure.

Helps

What does Liquorice help with? Indigestion (ongoing discomfort in the upper stomach): Folk use treated liquorice as a stomach soother. One small randomised trial of a liquorice extract reported fewer symptoms than placebo over 30 days . The trial was small and industry-linked, so this is a hint, not a settled answer. Sore throat and dry cough: European tradition used liquorice syrups and lozenges for hoarseness. A randomised trial found a liquorice gargle before surgery cut sore throat afterwards. For everyday colds, the evidence is mostly the sweet, coating feel rather than proof of healing. Mouth ulcers (small sores inside the mouth): Liquorice patches and pastes have been tried for these sores. A few small studies report less pain and faster healing. The studies are small and not well replicated. Heartburn and acid reflux: DGL chewables are widely sold for reflux. Trial support is thin and dated. Any relief is likely short-lived and does not treat the cause. Stomach and duodenal ulcers (DGL form): DGL was studied for ulcers in the 1970s and 1980s, before modern acid-blocking drugs. Those studies are old and hard to judge today. Proven drug treatments now exist, so ulcers need a doctor, not self-treatment. Tiredness and low blood pressure (traditional claim only): Liquorice does raise blood pressure, which is why it was once given for faintness. It is sometimes marketed for "adrenal fatigue", which is not a recognised medical diagnosis. Using liquorice this way risks the very harms listed on this page.

Liquorice

Quick Facts

  • What it is: The sweet root of Glycyrrhiza glabra, used in European folk medicine for coughs and stomach upsets and still common in sweets and teas.
  • Main uses: Indigestion, Sore throat and dry cough, Mouth ulcers, Heartburn
  • Active ingredients: Glycyrrhizin (glycyrrhizic acid), Glycyrrhetinic acid, Liquiritin, Isoliquiritigenin, Glabridin
  • Forms: Dried root and root powder, Tea bags and tea blends, Tinctures and liquid extracts, Capsules and tablets, DGL chewable tablets, Lozenges and syrups
  • Time to effect: Throat soothing is immediate; stomach trials ran 2 to 4 weeks.
  • Side effects: Raised blood pressure, low potassium, swelling and heart rhythm problems with regular use.
  • Pregnancy & breastfeeding: Avoid in pregnancy and while breastfeeding.

Educational information, not medical advice — ask your doctor or midwife.

What is Liquorice?

Liquorice is the root of Glycyrrhiza glabra, a small legume shrub. In German it is called Süßholz, meaning "sweet wood". The dried root and its extracts go into sweets, teas, cough syrups and capsules.

European folk healers reached for it mainly for coughs, sore throats and upset stomachs. Long use in a tradition is not proof that a remedy works. It is also not proof that it is safe.

Honest verdict: human evidence for benefit is thin and comes from a few small trials. The harm side is better proven than the benefit side.

Glycyrrhizin, the sweet compound in the root, can raise blood pressure and drop potassium (a key body salt). That effect is well documented in people, and it is dose related.

How does Liquorice work?

The best-proven action of liquorice in people is on salt and water balance, and it is not a wanted one.

The gut turns glycyrrhizin into glycyrrhetinic acid. In people, this blocks a kidney enzyme (a helper protein) that normally switches off cortisol, a stress hormone. The body then holds sodium and water and loses potassium.

This is why blood pressure can rise, ankles can swell and muscles can weaken. The effect builds with daily use.

The soothing claims are less certain. In test tubes and animal work, liquorice compounds appear to calm inflammation and coat irritated tissue.

In lab tests, some compounds slow Helicobacter pylori, a stomach bug linked to ulcers. Whether that happens inside a person's stomach is not established.

DGL stands for deglycyrrhizinated liquorice, which has most glycyrrhizin stripped out. The idea is to keep the soothing feel without the blood pressure risk. Human proof that DGL helps ulcers or indigestion is limited and mostly old.

What forms does Liquorice come in?

The key question with any form is how much glycyrrhizin it carries, and that varies hugely.

Dried root pieces and root powder are brewed as tea or chewed.

Teabags and cut-root blends appear in many cough and stomach teas, often mixed with other herbs.

Liquid extracts and tinctures are concentrated. Strength differs from maker to maker.

Capsules and tablets often state a glycyrrhizin amount on the label. That number is worth reading.

DGL chewable tablets have most of the glycyrrhizin removed. They are sold for stomach complaints.

Liquorice sweets and salty liquorice count too. So do some pastis-style drinks, herbal cough syrups and chewing tobaccos. People often forget these add up.

Gels and creams with glabridin are sold for skin tone. Human evidence for that use is weak.

Where it comes from:

Liquorice has one of the longest records of any European herb. Greek and Roman writers described the sweet root, and it later filled monastery gardens.

In German-speaking lands it was known as Süßholz. Bamberg in Bavaria grew it on a large scale for centuries.

Folk use centred on dry coughs, hoarseness, sore throats and sour stomachs. It was boiled into black sticks, syrups and lozenges.

Apothecaries also used it to mask the taste of bitter medicines. That habit carried into modern pharmacy.

From the 1900s it became a sweet as much as a medicine, especially in the Netherlands and the Nordic countries. Its salt and water effect was only described by doctors in the mid-20th century, after cases of swelling and high blood pressure.

Who should avoid Liquorice?

  • Do not use liquorice supplements, strong teas or large amounts of sweets if you are pregnant; heavy use has been linked to early birth.
  • Do not use it while breastfeeding.
  • Do not use it if you have high blood pressure.
  • Do not use it if you have heart failure, an irregular heartbeat or any other heart disease.
  • Do not use it if you have kidney disease.
  • Do not use it if you have liver disease, such as cirrhosis (scarring of the liver) or hepatitis (liver inflammation).
  • Do not use it if you have low potassium (hypokalaemia), a salt imbalance in the blood.
  • Do not use it if you take a water tablet (diuretic) such as furosemide or bendroflumethiazide.
  • Never combine it with digoxin, a heart drug.
  • Do not use it if you take a heart rhythm drug such as sotalol or amiodarone.
  • Do not use it if you take steroid tablets such as prednisolone.
  • Do not use it if you have primary aldosteronism (a gland making too much of the salt hormone aldosterone).
  • Do not give liquorice supplements to children.
  • Avoid it if a doctor has put you on a low-salt diet for heart, kidney or blood pressure reasons.

When should you see a doctor?

Stop using it and see a doctor if you notice puffy ankles, hands or face, new headaches, muscle weakness or cramps, or unusual tiredness.

Get urgent medical help for chest pain, a racing or skipping heartbeat, fainting, or weakness so bad you cannot move a limb.

Also seek urgent help for dark brown urine with aching muscles, which can mean muscle breakdown.

If you have indigestion with weight loss, black stools, vomiting blood or trouble swallowing, see a doctor straight away rather than treating it yourself.

Is Liquorice legal where you live?

In the EU and UK, liquorice is an ordinary food and flavouring, and sweets above a set glycyrrhizin level must carry a liquorice warning on the label. In the United States it is allowed as a food flavouring, and supplements are sold without pre-approval for safety or effect.

Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.

Reviewed by the HealisticMD editorial team How we grade evidence →

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