Educational information, not medical advice — ask your doctor or midwife.
Prickly Ash is a small, thorny North American tree. Herbalists use the dried bark, and less often the berries. It is also sold as Northern Prickly Ash, Toothache Bush or Yellow Wood.
Chewing a piece of the bark makes the mouth tingle and go numb. That effect gave the tree its nickname. American folk healers and Eclectic doctors also used it as a warming remedy for cold hands, aching joints and slow digestion.
Here is the honest verdict. There are almost no human studies on Prickly Ash for any use. Long use in tradition is not proof that it works, and it is not proof that it is safe.
No one has shown in people how Prickly Ash works. The ideas below come from tradition and from laboratory work.
The bark holds alkaloids and coumarins, which are plant compounds. In test-tube studies, some of them slow bacteria and fungi. Whether that happens inside the body is not established.
The mouth tingling is real and easy to feel. It is thought to come from compounds that act on nerve endings in the lining of the mouth. This local effect says nothing about effects deeper in the body.
Tradition called the bark a stimulant that pushed blood to the hands and feet. That idea has never been tested in a proper trial.
Prickly Ash is sold mainly as dried bark. Tinctures, which are alcohol extracts, are the next most common form.
- Dried bark, cut or powdered, for tea - Tincture, taken in drops or a measured millilitre dose - Capsules of powdered bark - Blends for joints or circulation, mixed with other herbs - Berries, used far less often than the bark
Check the Latin name on the label. Northern Prickly Ash is Zanthoxylum americanum. Szechuan pepper and Southern Prickly Ash are related but different plants.
Native peoples in eastern North America used the bark for toothache and sore gums. Settlers copied the practice, and the name Toothache Bush stuck.
Eclectic doctors in the 1800s listed it as a warming stimulant. They gave it for rheumatism, cramps, sluggish digestion and cold hands and feet. Some added it to fever and cholera mixtures.
The bark appeared in the United States Pharmacopoeia in the nineteenth century and later dropped out. Herbalists in the United States and Britain still use it today, mostly in circulation blends.
Stop taking it and see a doctor if you get stomach pain, black stools, or bruising and bleeding that is new for you.
Also stop and get checked if you notice a rash, yellowing of the skin or eyes, or dark urine.
Get emergency help for swelling of the lips or throat, trouble breathing, or trouble swallowing. See a dentist about any toothache rather than numbing it for days.
In the United States it is sold as a dietary supplement. The FDA has not approved it as a medicine for any condition. In the UK and the EU it is sold as a food supplement, with no licensed herbal medicine status.
Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
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