Educational information, not medical advice — ask your doctor or midwife.
Sammotsuogonto (also romanised Sanmotsu-ogon-to) is a three-herb Japanese Kampo formula taken as a bitter tea or granule powder. It is best known for one narrow, distinctive complaint: a hot, burning feeling in the palms and soles, classically in women after childbirth. Some practitioners also use it for dry, itchy skin in people who feel hot and restless.
It is one of the 148 Kampo formulas approved for reimbursement by Japan's Ministry of Health, Labour and Welfare (MHLW), so in Japan it is usually supplied on prescription by a doctor rather than bought off a shelf.
The honest evidence position: this formula has centuries of documented traditional use, but we could not identify a published controlled human trial of it. Long traditional use tells you a remedy has been valued and observed; it is not proof that it works. Treat the two things as separate questions throughout this page.
No one has shown, in people, how this formula produces its traditional effect. What follows is theory, not established fact.
In Kampo terms, the formula is described as clearing "heat" that has become trapped while the body's fluids are depleted — which is why the classical picture is burning palms and soles rather than a general fever.
In laboratory terms, the three roots contain compounds that damp down inflammation and calm overactive immune signalling in cells and in animals. Baicalin and baicalein from Ogon (Scutellaria root) are the most studied of these.
Laboratory and animal findings do not reliably predict what happens in a person taking a diluted herbal decoction. Take the mechanism above as a plausible story that has not been tested in humans.
In Japan the usual form is a dried extract granule or fine powder, dispensed in single-dose sachets on prescription.
Other forms you may meet:
Raw herb decoction — the three sliced roots simmered in water and strained, prepared by a Kampo or Chinese medicine practitioner. Very bitter.
Extract tablets or capsules — less common, used by people who cannot tolerate the taste.
Outside Japan the formula is sold as a supplement in some markets. Those products are not covered by Japan's prescription standards, and the amount of actual herb in them varies a lot. If you buy one, choose a supplier that publishes third-party testing.
The formula traces to the classical Chinese text Jingui Yaolue (Essentials of the Golden Cabinet), attributed to Zhang Zhongjing around the 3rd century CE, where it appears for feverish heat in the limbs after childbirth.
Japanese Kampo physicians adopted it and kept it in regular use, widening it to burning palms and soles and to dry, itchy skin in people who run hot.
It survives today as one of the MHLW's 148 approved Kampo formulas, which is why Japanese doctors can prescribe it under national health insurance. It is used much less in modern Chinese practice than in Japan.
Stop taking it and get medical help the same day if your skin or the whites of your eyes turn yellow, your urine goes dark, or you feel deeply tired with pain under your right ribs. These can be signs of liver injury.
Stop and seek urgent care if you develop a dry cough, fever and breathlessness that come on over days or weeks. This can be interstitial pneumonia (inflammation deep in the lungs) and it needs rapid assessment.
See a doctor promptly if you have a fever after childbirth, rather than treating it yourself — it may be an infection.
Also see your doctor if a rash spreads or blisters, if your stomach upset does not settle, or if nothing has improved after four weeks.
Evidence grades and traditional-use labels are explained in our methodology. Nothing here is medical advice.
Reviewed by the HealisticMD editorial team How we grade evidence →
The published evidence for Sammotsuogonto is weak or absent. That usually means no controlled trial has tested it, not that a trial found it ineffective — the two are different, and we grade only what has been published.
What it is typically used for, usual dose, cautions, and the study behind it where real trial data exists.
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